I take one tablet daily for fibrocystic breast disease. I originally started on one a day which eliminated symptoms. But after just under a year some mild symptoms stated to come back. I got a small lump surrounded by very tender inflamation. I increased my dose to two tablets and the lump was completely gone within a few days!! Soon after I went back to one tab per day. I cannot express my gratitude enough that I found out about this product and the protection benefits of iodine. I had suffered from FBD for many years and got to the stage where I couldnt even hug my kids or my husband - it was so painful. I had a lump surgically removed which was completely unnecessary as taking the iodine would have eliminated it. I wish my surgeon had told me about the condition I had and that taking this would cure it. ** WARNING THOUGH I would cut back the dosage after 12-18 months though to half a tab or preferably stop for a while. IMO by then your body should have been completely saturated with the Iodine and you don't want it to start making your thyroid work overtime. It is supposed to be be safe for long term use but I would proceed long term with caution. You can always start taking it again later if needed. ALWAYS take with some magnesium and vitamin C! And make sure you get your thyroid checked regularly whilst taking this. If you have taken too much Iodine you will start to feel very jittery like you have had too much coffee and this is your thyroid working too hard.