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Energy metabolism, nutrient metabolism, red blood cell formation
Adults with busy schedules seeking daily energy metabolism support or those with low intake of B-rich foods.
Take 1 capsule 1 to 3 times daily with food; swallow whole and do not crush, mix, or blend.
Vegan; Non-GMO; Gluten Free; Contains: Corn
Niacin is converted to NAD and NADP, key cofactors that help cells produce energy and carry out redox reactions.
Caution: High doses may cause flushing or stomach discomfort; take with food to reduce irritation.
Benfotiamine is a fat-soluble form of thiamin that supports carbohydrate metabolism and helps generate cellular energy via the pyruvate dehydrogenase pathway.
Caution: May affect responses in people monitoring blood sugar; monitor how you feel when starting.
Pyridoxal-5'-phosphate is the active coenzyme form of B6 that supports amino acid metabolism and neurotransmitter synthesis.
Caution: Very high intakes over time may cause tingling or numbness; follow the suggested use.
Methylcobalamin supports methylation and red blood cell formation by acting as a cofactor in homocysteine and folate metabolism.
Caution: Can mask signs of low folate if taken alone; this formula includes folate to balance intake.
L-5-MTHF is the bioactive folate form that supports one‑carbon metabolism for DNA synthesis and methylation.
Caution: High folate intake may hide signs of low B12 status; this formula also supplies B12.
Active forms of B6, B12, and L-5-MTHF work together in methylation and homocysteine metabolism, while niacin and benfotiamine focus on cellular energy production and carbohydrate processing. This combination covers complementary pathways for nutrient metabolism and red blood cell formation.
Label Warning: Consult a physician before use if you are pregnant, nursing, have a medical condition, or are taking any medication.
Who should be cautious: People with corn allergies may be sensitive, as this product contains corn. Those sensitive to high-dose niacin or vitamin B6 may experience flushing or nerve-related concerns at high intakes; consider discussing dosing with a healthcare provider.
Storage: Store tightly sealed in a cool, dry place.
Many users report feeling more energetic and balanced, making it a regular part of their routine.
Most reviewers find it easy to digest without nausea or typical B-vitamin discomfort.
A few users mention the niacin level feels excessive and occasionally leads to digestive discomfort.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Magnesium and B vitamins may support energy production and reduce fatigue, promoting overall vitality and well-being.
AI generated. Not medical advice.
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Discussion: Advanced B Complex™" was designed to provide the most advanced forms of B vitamins in the most scientifically discerning ratios available to help in the formation of red blood cells. Advanced B Complex™ contains benfotiamine, a form of vitamin B1 that is more bioavailable than other forms of thiamin, as well as pyridoxal-5-phosphate (PSP), methylcobalamin and L-5-methyltetrahydrofolate, bio-active forms of vitamin B6, B12 and folic acid respectively which aids in the maintaining the body's ability to metabolize nutrients.
Take 1 capsule 1-3 times daily with food, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules. Swallow capsules whole.
Microcrystalline cellulose, dicalcium phosphate, capsule (hypromellose and chlorophyll), silicon dioxide, sodium stearyl fumarate, ethylcellulose dibutyl sebacate, mannitol (corn).
This product contains corn.
Do not use if safety seal is broken.
Store tightly sealed in a cool, dry place.
Consult your physician before use if you are pregnant, lactating, have a medical condition, or are taking any medication. Keep out of reach of children.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||||
| Serving Size: 1 Capsule | ||||
| Servings Per Container: 90 | ||||
| Amout Per Capsule | % Daily Value | Amount Per Day (3 capsules) | % Daily Value | |
| Thiamin (B1 as Benfotiamine) | 33 mg | 2,750% | 100 mg | 8,333% |
| Riboflavin (B2 as Riboflavin-5-phosphate sodium) | 2.5 mg | 192% | 7.5 mg | 577% |
| Niacin (Vitamin B3) | 118 mg | 737% | 353 mg | 2,206% |
| B6 (as Pyridoxal-5'-phosphate) | 33 mg | 1,941% | 100 mg | 5,882% |
| Folate acid (as calcium L-5 MTHF) | 555 mcg DFE* (33 mcg folic acid) | 139% | 1,665 mcg DFE* (1,000 mcg folic acid) | 417% |
| B12 (as Methylcobalamin) | 333 mcg | 13,875% | 1,000 mcg | 41,667% |
| Biotin | 167 mcg | 556% | 500 mcg | 1,667% |
| Pantothenic acid (B5 as calcium D-pantothenate, Pantethine) | 100 mcg | 2,000% | 300 mg | 6,00% |
| Choline bitartrate | 80 mg | 15% | 240 mg | 44% |
| Inositol (as inositol, inositol hexanicotinate) | 131 mg | † | 393 mg | † |
| †Daily Value not established. *Dietary Folate Equivalent. | ||||
