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Bone health; Calcium balance; Cardiovascular wellness; Immune support
Adults with limited sun exposure or low dietary intake of vitamin K–rich foods seeking simple daily bone and calcium balance support.
Take 1 tablet once daily, preferably with a meal that contains some fat to support absorption of fat-soluble vitamins.
Vegetarian; Gluten Free; Free from synthetic colors and preservatives; Free from milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, and sesame.
Vitamin D3 is converted to its active form, which helps the intestines absorb calcium and supports calcium balance for bones and muscles.
Caution: High intakes may be unnecessary if you already take vitamin D; consider total daily intake from all sources.
Vitamin K1 acts as a cofactor for enzymes that activate proteins needed for normal blood clotting and calcium binding in tissues.
Caution: Vitamin K interacts with warfarin and similar anticoagulant medications because it affects clotting proteins.
MK-4 helps carboxylate osteocalcin and matrix Gla protein, which may direct calcium into bones and away from soft tissues.
Caution: Use caution with anticoagulant medications due to vitamin K activity affecting clotting regulation.
MK-7 provides a longer-lasting form of vitamin K2 that activates calcium-regulating proteins involved in bone and vascular health.
Caution: Those on anticoagulant therapy should consult a healthcare professional because vitamin K can influence INR control.
Vitamin D3 increases intestinal calcium absorption, while K1 and K2 activate proteins that help guide calcium into bone matrix. The inclusion of both MK-4 and MK-7 covers short- and longer-acting K2 forms to support ongoing activation of calcium-regulating proteins.
Who should be cautious: People taking anticoagulants like warfarin may need to be cautious due to vitamin K content. People with conditions affected by high calcium levels or those taking high-dose vitamin D should discuss use with a healthcare provider. If you are on medications that may interact with vitamin K, consult a healthcare provider before use.
Many users mention the small tablet size is simple to take daily.
Customers say the D3 and K2 combo feels effective for daily bone and immune needs, especially in low-sun seasons.
A few reviews imply results depend on personal response and routine.
Extensive studies of vitamins D3 and K2 in calcium metabolism indicate these two vitamins have a synergistic relationship in supporting bone strength and cardiovascular health. Vitamin D3 is also recognized for its role in immune health, while vitamin K2 is known to help direct calcium to bones rather than to arteries and joint spaces.
One tablet daily.
Keep tightly closed in a cool, dry place. Keep out of reach of children.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Amount Per Serving | %Daily Value | |
| Vitamin D (as Cholecalciferol [D3]) | 62.5 mcg (2500 IU) | 313% |
| Vitamin K (as phylloquinone [K1]) | 120 mcg | 100% |
| Vitamin K (as menatetrenone [K2, MK-4]) | 90 mcg | † |
| Vitamin K (as menaquinone [K2, MK-7]) (K2VITAL®) | 30 mcg | † |
| †Daily Value not established. | ||
Microcrystalline cellulose, organic rice bran extract, hydroxypropyl methylcellulose, silica, vegetable cellulose.
Free from synthetic: colors, preservatives.
Free from milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy and sesame.
