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Mood support; Emotional well-being; Stress support
Adults with high-stress, busy lifestyles or those seeking mood and emotional well-being support in daily routines.
Take 4 capsules daily with food; you may take up to 8 capsules daily as needed. Taking with a meal can improve tolerance, and evening use may feel more calming for some due to possible drowsiness.
Dairy Free; Gluten Free; Sugar Free; Corn Free; Soy Free; No Artificial Coloring; Nut Free; Egg Free; Yeast Free; No Artificial Flavoring
5-HTP is a direct precursor to serotonin, which the body converts via decarboxylation to support serotonin levels in the brain.
Caution: May cause drowsiness or gastrointestinal discomfort; avoid combining with antidepressants or MAOIs due to risk of excessive serotonin.
Saffron constituents like safranal and crocin are studied for modulating neurotransmitter signaling, which may influence mood perception.
Caution: May cause mild digestive upset in some people; use caution with other mood-support supplements due to overlapping effects.
Vitamin B6 acts as a coenzyme for aromatic L-amino acid decarboxylase, a key step in converting 5-HTP to serotonin.
Caution: High intakes may cause tingling or numbness in sensitive individuals; take with food to reduce nausea.
Methylfolate donates methyl groups for one-carbon metabolism, supporting synthesis of neurotransmitters including serotonin.
Caution: Consult a healthcare professional if using high-dose methyl donors or if you have MTHFR concerns, as sensitivity to methyl forms can occur.
Vitamin B12 supports methylation pathways and nerve function, which are involved in neurotransmitter synthesis and signaling.
Caution: High-dose B12 may cause restlessness in some people; those with B12-sensitive acne may prefer lower doses.
5-HTP supplies the direct building block for serotonin, while vitamin B6 supports the enzymatic conversion of 5-HTP into serotonin. Methylfolate and methylcobalamin back one‑carbon and methylation pathways that underlie neurotransmitter synthesis. Saffron extract is studied for modulating neurotransmitter activity, complementing serotonin pathway support.
Label Warning: Do not use if taking antidepressant or monoamine oxidase inhibitor medications. Not recommended during pregnancy.
Who should be cautious: People taking selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, or other serotonergic drugs may have a risk of serotonin-related side effects with 5-HTP; discuss with a healthcare provider before use. Individuals sensitive to saffron or with low blood pressure may need caution. Because this product contains 5-HTP, it is recommended to consult a healthcare provider before combining with medications that may interact.
Storage: Use contents within 45 days after opening. Store at room temperature in a dry place.
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Ashwagandha may help balance stress levels and promote relaxation, making it a great partner for stress relief formulas.
AI generated. Not medical advice.
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Serotonin Mood Support is one of the best supplements for mood. With a comprehensive blend of clinically studied ingredients designed to boost your brain’s production of serotonin, this powerful formula can increase calm, decrease anxiousness, and promote positive mood.
Take 4 capsules daily with food, maximum 8 capsules daily.
Vegetable cellulose (vegetarian capsule), microcrystalline cellulose, magnesium stearate, silicon dioxide.
Do not use if currently taking antidepressant or monoamine oxidase inhibitor medications. Not recommended during pregnancy.
Use contents within 45 days after opening. Keep out of reach of children. Store at room temperature in a dry place. Do not use if clear neck seal is broken or missing.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 4 Capsules | ||
| Servings Per Container: 30 | ||
| Amount Per Serving | %Daily Value* | |
| Vitamin B6 (as pyridoxine HCI & pyridoxal-5-phosphate) | 20 mg | 1,176% |
| Folate (as Quatrefolic® 5-methyltetrahydrofolate, glucosamine salt) | 400 mcg DFE1 | 100% |
| Vitamin B12 (as methylcobalamin) | 500 mcg | 20,833% |
| Satiereal® Saffron extract (Crocus sativus, stigma) [standardized to 0.34% (0.6 mg) safranal] | 177 mg | † |
| 5-Hydroxytryptophan (5-HTP) | 100 mg | † |
| †Daily Value not established. | ||
| 1DFE = Dietary Folate Equivalents | ||
