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Sleep support, Relaxation, Calm mood before bedtime
Adults with busy schedules who want simple nighttime wind-down support and people who prefer a timed-release sleep formula.
Adults take 1 tablet 30 minutes before bedtime; avoid alcohol and activities requiring alertness after use. If sensitive, consider starting on a night with ample sleep time.
Formulated without milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, sesame ingredients.
Melatonin signals the body’s internal clock that it is nighttime, which may help regulate the sleep-wake cycle and promote readiness for sleep.
Caution: May cause drowsiness; avoid driving, alcohol, or operating machinery after taking because it can impair alertness.
5-HTP is converted to serotonin, which may promote relaxation and support a calm mood before sleep.
Caution: Do not combine with serotonergic medications or other 5-HTP/L-tryptophan supplements due to risk of excessive serotonin-like effects.
Vitamin B6 acts as a cofactor in neurotransmitter synthesis, including the conversion of 5-HTP to serotonin.
Caution: High intakes may cause tingling or numbness in rare cases; stay within suggested use.
Melatonin helps align the body’s sleep timing while 5-HTP supports serotonin levels for a calmer mindset before bed. Vitamin B6 serves as a cofactor to help convert 5-HTP into serotonin, reinforcing the relaxation pathway.
Label Warning: For adults only; not for individuals under 18. Not intended for insomnia or other sleep disorders. Consult a physician before use if taking medications for depression, migraine, Parkinson’s disease, or psychiatric disorders; if using tranquilizers or sedatives; if you have any medical condition; if pregnant or lactating; or if you have an autoimmune condition or a depressive disorder. May cause drowsiness; do not use when driving, operating heavy machinery, or consuming alcohol. Do not use with other supplements containing L-tryptophan or 5-HTP. Discontinue if adverse reactions occur. For occasional short-term use only. Use only as directed and do not exceed suggested use. Not a substitute for healthy sleep practices.
Who should be cautious: People taking SSRIs, SNRIs, MAOIs, triptans, or other serotonergic agents, or with mood disorders, should be cautious due to 5-HTP and the risk of serotonin-related effects. Those on sedatives or with sleep disorders, autoimmune conditions, pregnancy, or lactation should consult a healthcare provider before use. If combining with medications that may interact with 5-HTP, discuss with a healthcare provider first.
Storage: Store in a cool, dry place.
Many users say they fall asleep quicker and feel more relaxed with the melatonin and 5-HTP combo.
Several reviews mention improved sleep quality and waking feeling more refreshed.
A minority report feeling groggy the next day or not staying asleep all night.
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Lemon Balm may help reduce stress and anxiety, potentially enhancing the effectiveness of sleep formulas.
AI generated. Not medical advice.
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For A Great Night's Sleep
5-HTP -A naturally occurring amino acid that increases production of Serotonin.
Melatonin - A naturally occurring hormone produced by the brain to help the body manage the "Sleep Wake" Cycle.
Bi-Layer Controlled Release Tablet
Ingredients are released in stages to more effectively help you relax, fall asleep and stay asleep.
Natrol® Advanced Sleep Melatonin + 5-HTP
Calm the Mind - Helps calm the mind so you can relax before falling asleep.
Fall Asleep Faster - Melatonin releases quickly to help you fall asleep faster.
Sleep Support Through the Night - A controlled release of Melatonin helps you sleep through the night.
This product is helpful for occasional sleeplessness.
∧ Nielsen, xAOC, 52 Weeks ending 03/29/2025, sleep aid supplements.
Due to Japanese Customs regulations, a maximum of 1 bottle per order can be imported to Japan.
Adults, take 1 tablet 30 minutes before bedtime.
Microcrystalline cellulose, hypromellose, silicon dioxide, stearic acid, maltodextrin, beet root extract (color), cellulose gum, magnesium stearate, methylcellulose, glycerin.
Formulated without milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, sesame ingredients.
Not intended for individuals under the age of 18 years. This product is not intended to treat insomnia or other sleep disorder. Consult a physician before using this product if taking medication, including drugs for depression, migraine, Parkinsons disease or psychiatric disorder, or if you are using any tranquilizers or sedatives, have any medical condition, are pregnant or lactating, have an autoimmune condition or depressive disorder. Melatonin may cause drowsiness or sleepiness, do not take when driving or operating heavy machinery, or consuming alcohol. Do not use with other supplements containing L-Tryptophan or 5-HTP. If adverse reactions occur, discontinue use. For occasional short-term use only. Use only as directed and do not exceed suggested use. This product should never substitute healthy sleep practices.
Keep out of reach of children.
Store in a cool, dry place.
Do not use if safety seal is damaged or missing.
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Servings Per Container: 60 | ||
| Amount Per Serving | %DV | |
| Vitamin B-6 (as Pyridoxine Hydrochloride) | 10 mg | 588% |
| Calcium (as Dibasic Calcium Phosphate) | 97 mg | 7% |
| 5-HTP (5-Hydroxytryptophan) (from Griffonia simplicifolia) (seed) | 50 mg | * |
| Melatonin | 6 mg | * |
| *Daily Value (DV) not established. | ||
